Packed red blood cells are washed to significantly reduce the quantity of various plasma proteins or other substances that can cause adverse reactions. This product contains more than 75% of the red blood cells that were in the original product. The washing removes almost all other residual substances (anticoagulant, platelets, leukocytes, and potassium).

The washing method used at Héma-Québec is done in a closed circuit, and the suspension medium is an injectable AS-3 (additive) solution as a preservative.

Action

Washed red blood cells have a similar function and post-transfusion survival as AS 3/SAGM packed red blood cells.

Main indications

Washed red blood cells are indicated for recipients who are IgA deficient and previously had a major allergic reaction following transfusion of labile blood products.

The indication applies to recipients who have major allergic reactions to other plasma proteins. Washed red blood cells are indicated for recipients who are IgA deficient with the presence of anti-IgA antibodies and previously had a major allergic reaction following transfusion of labile blood products.

Contraindications

The contraindications are the same as those for AS-3/SAGM packed red blood cells.

Dosage and administration

The dosage and administration are the same as those for AS-3/SAGM packed red blood cells.

The transfusion must be completed within four hours after the product leaves the controlled environment.

Storage

Red blood cells washed in a closed circuit have a 7-day shelf life in AS-3 when kept between 1°C and 6°C unless irradiated: refer to the red blood cell label.

In the event of a discrepancy between the information on this page and what is in the Circular of information, the latter will take precedence.